• Wesiana Heris Santy
Keywords: Diabetes, Mellitus, ulkus, kaki, tekanan, negatif


Complications often experienced by people with diabetes are complications in the feet ( 15 % ) called diabetic foot ( Akhtyo , 2009) . Where the injury to the leg if not treated properly will lead to infections and ultimately need to be amputated .The purpose of writing articles is to review and discuss the evidence-based literature bersadarkanpraktice of Negative Pressure Wound Therapy Effectiveness ( NPWT ) ) on the healing of diabetic foot ulcers.One technology that is used to prevent and avoid lower limb amputation is the technique of negative pressure or Negative Pressure Wound Therapy ( NPWT ) ) . This negative pressure technique has grown rapidly and now has been widely used in many countries , especially in Western European countries ( Germany ) and the United States . Negative pressure technique has the advantage that it is relatively cheaper cost than the use of hyperbaric oxygen . Results obtained by several studies that the use of NPWT may improve wound healing process through efforts to create a moist wound environment and decrease edema that becomes optimal wound healing , throw that out of the wound exudate so that the protease enzyme in the exudate also go wasted , this enzyme is known to interfere wound healing process . The other benefit is that it can stimulate cell growth by increasing angiogenesis physically , so that the growth of new cells will be maximal


Andros, George, (2005). Consensus Statement on Negative Pressure Wound Therapy (V.A.C.® Therapy) for the Management of Diabetic Foot Wounds. OWM Jounal. June 2005. didownload pada tanggal 3 Juni 2013.
Blume, Peter A. (2008). Comparison of Negative Pressure Wound Therapy Using Vacuum-Assisted Closure With Advanced Moist Wound Therapy in the Treatment of Diabetic Foot Ulcers. Diabetes Care Journal. April 2008. Didownload pada tanggal 12 Juni 2010
C. Smeltzer, Susan. (2002). Buku Ajar Keperawatan Medikal-Bedah Brunner & Suddarth Ed. 8.Jakarta: EGC.
Claire, Michael P. et al (2002). Experience with Vacuum Assited Closure Negative Pressure Technique in the Treatment of Non-healing Diabetic and Disvasular Wound. American Orthopaedic and Ankle Society. Ink.ência com a Técnica de Pressão Negativa do V.A.C. .pdf. didownload pada tanggal 12 Juni 20103
Deva, AK., et al (2000). Topical Negative Pressure in Wound Management. Med J Aust. 2000 Aug 7;173(3):128-31. pubmed/10979377. didownload pada tanggal 12 Juni 2013.
Etöz, Abdullah, et al. (2004). The Use of Negative Pressure Wound Therapy on Diabetic Foot Ulcers: A Preliminary Controlled Trial,, didownload pada tanggal 17 Juni 2013
Kilpadi, Deepak V. et al (2006). Composition of Wound Fluid From Pressure Ulcers Treated With Negative Pressure Wound Therapy Using V.A.C. Therapy in Home Health or Extended Care Patients: A Pilot Study,, didownload pada tanggal 15 Juni 2013
Kirby, Michael. (2007). Negative Pressure Wound Therapy. The British Journal of Diabetes & Vascular Disease., didownload pada tanggal 15 Juni 2013.
Lanywati, Endang (2007). Diabetes Melitus Penyakit Kencing Manis. Yokyakarta: Kanisius.
Lavery, Lawrence A. et al. (2007).A comparison of diabetic foot ulcer outcomes using negative pressure wound therapy versus historical standard of care., didownloadpadatanggal2 Juni 2013
Mouësa C.M. et al (2006).Comparing conventional gauze therapy to vacuum-assisted closure wound therapy: A prospective randomised trial., didownload pada tanggal 7Juni 2013
Sudoyo, Aru dkk (2006). Buku Ajar Ilmu Penyakit Dalam. Jilid III Edisi IV. Jakarta : Pusat Penerbitan Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia
Sujono & Sukarmin (2008). Asuhan Keperawatan pada Pasien dengan Gangguan Eksokrin & Endokrin pada Pankreas. Yogyakarta: Graha Ilmu.
Tjokronegoro, Arjatmo (1996). Buku Ajar Ilmu Penyakit Dalam Jilid I. Jakarta: Balai Penerbit FKUI.
Ubbink DT, et al (2008). Topical negative pressure for treating chronic wounds. 2801%2993547-7/abstract, didownloadpadatanggal12Juni 2013
Vikatama, P., (2008). Negative Pressure Wound Therapy: a Systematic Review on Effectiveness and Safety. didownload pada tanggal 18 Juni 2013